Preimplantation Genetic Testing in Women of Advanced Maternal Age
ConditionInfertility, Female
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age35-40
SponsorGenomic Prediction Inc.
About this trial
The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40 years of age.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Women undergoing IVF of between 35 and 40 years of age at IVF cycle start
Utilization of Intracytoplasmic Sperm Injection ICSI
Utilization of ejaculated or testicular sperm
Utilization of autologous or donor sperm
Disqualifiers
Patients with anovulatory Polycystic ovarian syndrome (PCOS)
Utilization of donor oocytes
Utilization of gestational carrier
Recurrent Pregnancy Loss (RPL) defined as ≥ 3 consecutive miscarriages
Trial design
Design model
Parallel
Treatments tested in this trial
Preimplantation genetic testing for aneuploidy (PGT-A)
Procedure/Surgery24-chromosome screening for aneuploidy in the preimplantation embryo (blastocyst stage)
Treatment groups
240 Participants
are divided into 2 treatment groupsGroup A: PGT-A transferExperimental treatment 1 intervention
Group B: Untested blastocyst transferNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Ongoing pregnancy rate
Number of patients who experience an ongoing pregnancy rate (\>20 weeks of gestation) after their first embryo transfer
Time frame
Up to 18 monthsSecondary outcomes
1
Miscarriage rate
Number of patients who experience a miscarriage after their first embryo transfer
Time frame
Up to 18 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov