Preliminary Study on the Diagnostic Value Comparison of 18F-FAPI-04 PET/CT and PET/MR in Gastric Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorHunan Cancer Hospital

About this trial

This project aims to comprehensively analyze the diagnostic efficacy of SUVmax, SUVean, TLG, MTV, etc. in gastric cancer through 18F-FAPI-04 PET/CT imaging combined with serum tumor markers and other methods, and construct a molecular imaging diagnostic model for gastric cancer; Next, analyze the diagnostic efficacy of 18F-FAPI-04 PET/CT and PET/MR multimodal imaging in evaluating SUVmax, PET/CT-PCI, and PET/MR-PCI for gastric cancer peritoneal metastasis, and construct a molecular imaging diagnostic model for gastric cancer peritoneal metastasis; Exploring the clinical value of 18F-FAPI-04 PET/CT and PET/MR imaging in the diagnosis and staging of gastric cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age over 18 years old;

Diagnosed as a patient with gastric cancer;

Receive FAPI PET/CT and FDG PET/CT imaging within one week;

Perform serum tumor marker testing one week before and after scanning

Disqualifiers

History of other malignant tumors;

Patients with severe infections, severe underlying diseases such as heart, kidney, and liver;

Patients with contraindications for PET-CT examination, poor physical condition, and inability to tolerate the examination;

Patients with unorganized pathology or incomplete clinical data

Trial population

Gastric cancer

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • The clinical value of 18F-FAPI-04 PET/CT and PET/MR imaging in the diagnosis and staging of gastric cancer

    Diagnostic test

    The clinical value of 18F-FAPI-04 PET/CT and PET/MR imaging in the diagnosis and staging of gastric cancer

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

18F-FAPI-04 PET imaging diagnosis of gastric cancer detection rate

Exploring the feasibility of using targeted fibroblast activation protein (FAP) PET/CT imaging for gastric cancer; Compare the advantages and disadvantages of 18F-FAPI-04 and 18F-FDG in gastric cancer imaging, explore the clinical application value of 18F-FAPI-04 PET/CT in gastric cancer imaging, and construct a molecular imaging diagnostic model for gastric cancer

Time frame
2 years

Secondary outcomes

1

Detection rate of peritoneal metastasis in gastric cancer

Comparison of the diagnostic value of 18F-FAPI-04 PET/CT and PET/MR for peritoneal metastasis of gastric cancer, and construction of a molecular imaging diagnostic model for peritoneal metastasis of gastric cancer

Time frame
2 years

Other outcomes

Sponsors and contacts

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