Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life. Surgical treatment with Holmium Laser Enucleation of the Prostate (HoLEP) or Transurethral Resection of the Prostate (TURP) is often recommended when medical therapy is insufficient.
This prospective observational study aims to evaluate whether preoperative anxiety, depression, and surgical fear influence postoperative functional outcomes, urinary continence, erectile function, and patient satisfaction in patients undergoing HoLEP or TURP for BPH. Participants will complete validated psychological and functional questionnaires before surgery and during postoperative follow-up visits at 1 and 3 months. The study will also assess changes in psychological status after surgery and compare outcomes between HoLEP and TURP patients.
The findings may help improve preoperative patient counseling and identify patients who could benefit from additional psychological support before surgery.
Male patients aged 50 years or older
Diagnosis of benign prostatic hyperplasia (BPH)
Scheduled to undergo HoLEP or TURP
Ability to understand and complete study questionnaires
History of severe psychiatric disorder
Active psychiatric treatment
Neurogenic bladder or neurologic voiding dysfunction
Diagnosis of prostate cancer
Male patients aged 50 years or older with benign prostatic hyperplasia (BPH) who are scheduled to undergo Holmium Laser Enucleation of the Prostate (HoLEP) or Transurethral Resection of the Prostate (TURP) at Hitit University Erol Olcok Training and Research Hospital and who provide written informed consent.
Cohort
Prospective
Holmium Laser Enucleation of the Prostate (HoLEP)
Procedure/SurgeryStandard HoLEP procedure for treatment of benign prostatic hyperplasia.
Transurethral Resection of the Prostate (TURP)
Procedure/SurgeryStandard TURP procedure for treatment of benign prostatic hyperplasia.
Change in International Prostate Symptom Score (IPSS)
Association between preoperative anxiety levels and postoperative functional improvement measured by changes in International Prostate Symptom Score (IPSS). IPSS scores range from 0 to 35, with higher scores indicating more severe lower urinary tract symptoms. Change from baseline to postoperative 3 months will be evaluated.
Change in IIEF-5 Score
Change in International Index of Erectile Function-5 (IIEF-5) score. Scores range from 5 to 25, with higher scores indicating better erectile function.
Urinary Incontinence Assessed by ICIQ-SF
Urinary continence assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). Scores range from 0 to 21, with higher scores indicating more severe urinary incontinence.
Change in HADS Score
Change in Hospital Anxiety and Depression Scale (HADS) score. Total scores range from 0 to 42, with higher scores indicating greater anxiety and depressive symptoms.
Change in STAI Score
Change in State-Trait Anxiety Inventory (STAI) score. Scores range from 20 to 80, with higher scores indicating greater anxiety levels.
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