Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorNecmettin Erbakan University

About this trial

This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for post-induction hypotension in adult patients undergoing elective non-cardiac surgery under general anesthesia. Hemodynamic instability during anesthesia induction is a common and clinically important problem associated with adverse perioperative outcomes. Carotid Doppler ultrasonography provides a rapid and non-invasive method for assessing hemodynamic status at the bedside. In this study, carotid Doppler measurements will be performed in the preoperative period and their association with post-induction hypotension will be analyzed. The results of this study may help identify patients at risk for hypotension and improve perioperative hemodynamic management.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patients aged 18-65 years

Disqualifiers

None

Trial population

Adult patients aged 18-65 years with American Society of Anesthesiologists (ASA) physical status I-II who are scheduled for elective non-cardiac surgery under general anesthesia will be included in this study.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

110 Participants
are grouped into 1 trial group
Group A: Elective Non-Cardiac Surgery Patients

Trial outcomes

Primary outcomes

1

Post-induction hypotension

Occurrence of post-induction hypotension after anesthesia induction, defined as either a decrease in mean arterial pressure (MAP) of ≥30% from baseline or a MAP \<65 mmHg sustained for at least 1 minute.

Time frame
From anesthesia induction until 10 minutes after tracheal intubation or until the start of surgery, whichever occurs first.

Secondary outcomes

1

Predictive performance of carotid Doppler parameters

Diagnostic accuracy of preoperative carotid Doppler parameters (carotid VTI and corrected carotid flow time \[ccFT\]) for predicting post-induction hypotension, including area under the receiver operating characteristic curve (AUC), sensitivity, specificity, and optimal cut-off values.

Time frame
From the initiation of anesthetic induction until 10 minutes after tracheal intubation or until surgical incision, whichever occurs first.

Other outcomes

Sponsors and contacts

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