Preoperative Performance Indicators, Preoxygenation and Oxygen Reserve Relationship
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAnkara City Hospital Bilkent
About this trial
The goal of this observational study is to evaluate the relationship between preoperative cardiopulmonary performance indicators and preoxygenation efficiency along with oxygen reserve depletion in patients scheduled for elective surgery under general anesthesia. The main questions it aims to answer are:
What is the relationship between Hand Grip Strength (HGS) and the time taken for end-tidal oxygen (EtO\_2) to reach 90% during preoxygenation? What is the relationship between the 6-Minute Walk Test (6MWT) distance and the Oxygen Reserve Index (ORI) depletion time during the apnea period?
Participants will be asked to perform the following tasks during their preoperative and intraoperative care:
Complete a 6-Minute Walk Test (6MWT) to determine preoperative functional capacity.
Perform a Hand Grip Strength (HGS) test using a calibrated hand dynamometer to measure muscle strength.
Undergo standardized preoxygenation with 100% oxygen via a tight-fitting face mask in the operating room while end-tidal oxygen (EtO\_2) and Oxygen Reserve Index (ORI) levels are continuously monitored.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Patients scheduled for elective surgery at Ankara Bilkent City Hospital, Department of Anesthesiology and Reanimation, who will undergo preoxygenation before anesthesia induction.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
120 Participants
are grouped into 1 trial groupGroup A: Surgical Patients Evaluated for Cardiopulmonary Performance
Trial outcomes
Primary outcomes
1
Preoxygenation Efficiency (EtO_2 Time)
The time taken for end-tidal oxygen (EtO\_2) to reach 90% during preoxygenation.
Time frame
From the initiation of preoxygenation (0 seconds) until the EtO_2 values reach 90% (typically within 3 to 5 minutes before anesthesia induction)2
Oxygen Reserve Depletion Time (ORI Time)
The time duration for the Oxygen Reserve Index (ORI) value to drop below 0.55.
Time frame
From the cessation of preoxygenation/initiation of apnea until the ORI drops below 0.55Secondary outcomes
1
Preoperative Functional Capacity (6MWT)
Total functional distance walked during the 6-minute walk test
Time frame
Preoperative period2
Preoperative Muscle Strength (HGS)
Muscle strength measured using a calibrated hand dynamometer (the highest value of three consecutive measurements using the dominant hand)
Time frame
Preoperative periodLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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