Preterm Birth Cohort Study in Guangzhou
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 18
SponsorGuangzhou Women and Children's Medical Center
About this trial
The Preterm Birth Cohort Study in Guangzhou (PBCSG) aims to explore the impact of genetic and environmental factors including life styles on preterm birth, to examine the interaction effect between these factors, and to follow up the short-term and long-term outcomes of preterm childrens.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Born before 37 weeks of gestation
Born in Guangzhou Women and Children's Medical Center
Intended to remain in Guangzhou for more than 3 years
Disqualifiers
Multiple birth
Stillbirth
With major congenital abnormalities
Trial population
The study population are childrens born before 37 weeks of gestation and their mothers in Guangzhou.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
- Other intervention
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Neurodevelopment at early childhood
Assessed by using the Gesell Developmental Schedules, which include adaptive, gross motor, fine motor, language, and social function domains. Higher score in each domain is considered a better outcome, while no more than 85 is defined as suspected development retardation
Time frame
At age of 1 yearSecondary outcomes
1
Intelligence quotient of offspring
Assessed by using Wechsler's Intelligence Scale for Children (WISC), which can generate a full scale intelligence quotient score and five primary index scores including verbal comprehension, visual spatial, fluid reasoning, working memory, and processing speed. Intelligence quotient ranges from 40 to 160,in which less than 70 is defined as mental retardation
Time frame
At age of 6 years old2
Height changes during childhood and adolescence
Measured by nurses in clinic using a standard tool
Time frame
At birth, age of 6 weeks, 6 months, 1 year, 3 years, 6 years, 12 years and 18 year3
Weight changes during childhood and adolescence
Measured by nurses in clinic using a standard tool
Time frame
At birth, age of 6 weeks, 6 months, 1 year, 3 years, 6 years, 12 years and 18 year4
Change of intestinal flora during early childhood
Assessed by analyses of stool samples
Time frame
At age of 6 weeks, 6 months, 1 year, 3 years, 6 years, 12 years and 18 years oldSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov