Prevalence of Central Neuropathic Pain After a Stroke in Patients Attending Post-stroke Consultations in the Île-de-France Region

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorFondation Hôpital Saint-Joseph

About this trial

Post-stroke pain is common, affecting 15-50% of patients and significantly impacting their quality of life, rehabilitation, and functional recovery. There are different types of post-stroke pain, including peripheral pain related to spasticity, shoulder pain, complex regional pain syndrome, and headaches, as well as central pain linked to brain lesions. Central Post-Stroke Pain (CPSP) is diagnosed when the pain has neuropathic characteristics (burning, cold, tightness, compression), possibly accompanied by allodynia, hyperesthesia, and sensory-motor disorders localized to the area affected by the stroke. CPSP disrupts sleep, impairs functional rehabilitation, and can lead to depression, anxiety, substance abuse, and cognitive disorders. The prevalence of CPSP varies, ranging from 1% to 35%, but it is likely underreported due to difficulties in detection caused by cognitive or communication issues, the clinical variability of CPSP, and its coexistence with other types of post-stroke pain.

CPSP often remains resistant to standard neuropathic pain treatments, such as anticonvulsants and antidepressants, which may cause side effects that reduce patients' autonomy and quality of life. Non-pharmacological therapies used in other chronic pain conditions may offer promising alternatives, but have not been widely studied in CPSP. Improved clinical characterization of CPSP patients is essential. Following a 2015 decree by the French Ministry of Health, post-stroke consultations are standardized, providing a good opportunity for systematic pain screening. The study proposes a systematic screening of different types of pain during post-stroke consultations, categorizing patients into three groups: those with CPSP, those with pain from another mechanism, and those without pain.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient aged ≥18 years

Patient attending a post-stroke consultation (3 to 6 months after the stroke)

Stroke confirmed by imaging (MRI or CT scan)

Francophone patient

Disqualifiers

Patient with cognitive or communication disorders preventing them from completing the questionnaires (as assessed by the investigator)

Patient under guardianship or curatorship

Patient deprived of liberty

Patient under judicial protection

Trial population

Post Stroke Patient

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Patient Reported Outcome (PRO)

    Other intervention

    after enrollment, patient will answer to several PRO to assess their pain and overall well-being after their stroke

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Central Pain

determine the prevalence of post-stroke central pain in patients recruited during post-stroke consultations conducted between 3 and 6 months after their stroke.

Time frame
enrollment

Secondary outcomes

Other outcomes

Sponsors and contacts

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