Prevalence of Fibromyalgia in Patients With Plaque Psoriasis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University
About this trial
This observational study aims to determine how common fibromyalgia syndrome and central sensitization are in adults with plaque psoriasis compared to healthy individuals. Plaque psoriasis is a chronic inflammatory skin disease that can affect the entire body, which may increase the risk of developing chronic pain conditions. Fibromyalgia causes widespread musculoskeletal pain, fatigue, and sleep disturbances, while central sensitization involves the central nervous system becoming highly sensitive to pain.
Researchers will evaluate 55 adult patients diagnosed with plaque psoriasis and 55 age- and sex-matched healthy volunteers at the Dermatology Outpatient Clinic at Assiut University Hospital. Participants will undergo a clinical examination to assess their psoriasis severity and will complete standardized questionnaires to evaluate pain intensity, fibromyalgia symptoms, central sensitization, and overall quality of life. The findings of this study may help doctors better understand these overlapping conditions to improve the early identification and management of pain in patients with psoriasis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients (≥18 years) with clinically diagnosed plaque psoriasis.
Both males and females.
Willing to participate and provide written informed consent.
For controls: Apparently healthy age- and sex-matched volunteers.
Disqualifiers
Patients with psoriatic arthritis or other inflammatory arthritis.
Patients with other diagnosed rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis).
Patients with previously diagnosed major depressive disorder or generalized anxiety disorder.
Patients with uncontrolled diabetes mellitus, heart failure, renal failure, or thyroid disorders.
Trial population
The study population consists of adult male and female patients (18 years of age and older) clinically diagnosed with plaque psoriasis who are attending the Dermatology Outpatient Clinic at Assiut University Hospital. It also includes a control group of apparently healthy, age- and sex-matched volunteers.
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
110 Participants
are grouped into 2 trial groupsGroup A: Patients with Plaque Psoriasis
Group B: Healthy Controls
Trial outcomes
Primary outcomes
1
Percentage of Participants Diagnosed With Fibromyalgia Syndrome
Fibromyalgia will be diagnosed according to the 2016 American College of Rheumatology (ACR) Diagnostic Criteria. This assessment combines two measures: the Widespread Pain Index (WPI), which assesses pain in 19 body regions with scores ranging from 0 to 19, and the Symptom Severity Scale (SSS), which evaluates fatigue, waking unrefreshed, cognitive symptoms, and other somatic symptoms with scores ranging from 0 to 12. For both scales, higher scores indicate worse symptom severity. The combined scores are used to establish a diagnosis of fibromyalgia.
Time frame
BaselineLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: