About this trial
To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development.
The aims of this study are :
* Assess the caries risk in childhood cancer survivors compared with a control group. * Assess the dental development defects risk in childhood cancer survivors compared with a control group.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
age below 10 at cancer diagnosis (for the CCS group).
Chemotherapy must have been used to treat the patient (For the CCS group).
The patient is 12 years old or older at the time of the follow-up appointment of the present study
Disqualifiers
A patient who was diagnosed and treated after 10 years old.
Patient below 12 years old at time of study recruitment
Patients with syndrome or diseases that involve teeth impairment*
Pregnant patient
Trial design
Parallel
Treatments tested in this trial
Clinical and radiographic dental examination
Diagnostic testcomplete clinical oral examination + intra-oral and panoramic x-rays
Treatment groups
Trial outcomes
Primary outcomes
Assessment of the caries experience by using the Decay Missing Filled Teeth score (DMFT)
Assess the impact of the chemotherapy agents on the risk of ulterior caries development
Secondary outcomes
Assessment of the prevalence of dental development defects (DDD)
Assess the impact of the chemotherapy agents on the risk of ulterior dental development defect
Sponsors and contacts
Click on the lead sponsor to view all of their trials.