PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
ConditionTransient Global Amnesia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Strasbourg, France
About this trial
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at present. A recent study on a small sample size (N=29) highlighted an association between obstructive sleep apnea syndrome and amnesic stroke. Our study seeks to confirm or refute these results on a larger cohort (N=200-250). A better understanding of the pathophysiological processes involved would open up new therapeutic avenues.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
The stroke must have been documented and reported by a competent witness present during the stroke.
Anterograde amnesia during the stroke.
Absence of vigilance, personality, and cognitive disorders other than memory disorders (aphasia, apraxia, etc.).
Absence of focal neurological symptoms during the episode and its aftermath.
Disqualifiers
Patients who have expressed opposition to the retrospective reuse of their data for scientific research purposes.
Patients with active epilepsy
Patients with recent head trauma
Patients with an MMS < or equal to 25
Trial population
Adult patients seen for consultation in the Neuropsychology Department of Strasbourg University Hospital between March 1, 2015 and December 31, 2021 following an episode of amnestic stroke meeting the Hodges and Warlow criteria.
Trial design
Design model
Case-only
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
To assess the prevalence of obstructive sleep apnea syndrome in patients who have experienced an amnestic stroke.
Presence or absence of obstructive sleep apnea syndrome reported by a witness present during the stroke.
Time frame
Within the last 2 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov