PrEventing PostoPERative Pulmonary Complications by Establishing a MachINe-learning assisTed Approach

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBritta Trautwein

About this trial

Postoperative pulmonary complications (POPC) are common after general anaesthesia and are a major cause of increased morbidity and mortality in surgical patients. However, prevention and treatment methods for POPC that are considered effective, tie up human and technical resources. The aim of the planned research project is therefore to enable reliable identification of high-risk patients on the basis of a tailored machine learning algorithm using perioperative clinical routine data and sonographic imaging data collected in the recovery room. The randomized clinical trial will include 512 patients undergoing elective surgery in general anaesthesia. The primary outcome will be the development of POPC. The goal of the study is to detect postoperative pulmonary complications before they become clinically manifest.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

adult patients

elective, surgical procedure

general anaesthesia

Disqualifiers

patients younger than 18 years of age

outpatient surgery

postoperative admission to intensive care unit

Trial population

adult patients in a university hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

512 Participants
are grouped into 1 trial group
Group A: Development of the machine learning model

Trial outcomes

Primary outcomes

1

Number of patients with postoperative pulmonary complications (POPC)

POPC according to criteria by the StEP-collaboration. This includes a clinical examination and interview of the patients on postoperative day 1,3 and 7.

Time frame
postoperative day 7 or day of discharge

Secondary outcomes

Other outcomes

Sponsors and contacts

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Britta Trautwein

Lead sponsor

University Hospital Ulm

Sponsor institution