About this trial
The number of people with allergies has been steadily increasing over the years. Symptoms in infants, such as bronchiolitis, gastroesophageal reflux, eczema, or atopic dermatitis, can be early warning signs of allergies in childhood. Given the rising prevalence of allergies and the number of children affected by bronchiolitis, it is worth investigating whether the presence of allergies in parents is associated with a higher likelihood of developing bronchiolitis in childhood.
To determine the incidence of respiratory distress in infants with at least one allergic parent compared to infants with no allergic parents at 12 months of age.
Parents will be asked to complete a questionnaire at two time points: at 6 months and at 12 months of age.
The incidence of bronchiolitis during the first year of life is higher among infants with at least one parent who has allergies.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Newborns delivered at Amiens Picardie University Hospital, Full-term newborns, i.e.,
≥ 37+0 weeks of gestation (SA),
Newborns whose mothers are of legal age and capable of understanding, reading, and speaking French or, failing that, who have someone in their immediate circle capable of understanding, reading, and speaking French;
Newborns whose mothers are enrolled in the social security system;
Disqualifiers
Premature newborns
Newborns whose parents refused to allow them to participate in the study
Newborns from multiple pregnancies
Newborns with malformations diagnosed prenatally or immediately after birth (in the delivery room)
Trial design
Parallel
Treatments tested in this trial
questionnaire
Other interventionquestionnaire will be emailed when the child is 6 months old and again when the child is 12 months old. These questionnaires include questions about any health issues that have arisen since the last contact, the number and reason for the child's hospitalizations (if applicable), the child's vaccinations, and the child's diet.
Treatment groups
Trial outcomes
Primary outcomes
incidence of respiratory distress at 12 months of age in infants
incidence of respiratory distress at 12 months of age in infants with at least one allergic parent, compared with those whose parents have no history of allergy, at 12 months
Secondary outcomes
incidence of respiratory distress at 6 months of age in infants
incidence of respiratory distress at 6 months of age in infants with at least one allergic parent, compared with those whose parents have no history of allergy
incidence of respiratory distress when both parents are allergic
determine the incidence of respiratory distress when both parents are allergic, according to the type of allergy (respiratory, food, drug-related, or other) compared to a control group (no allergy for both parents)
incidence of respiratory distress when both parents are allergic
determine the incidence of respiratory distress when both parents are allergic, according to the type of allergy (respiratory, food, drug-related, or other) compared to a control group (no allergy for both parents)
incidence of respiratory distress requiring hospitalization when only one parent is allergic)
incidence of respiratory distress requiring hospitalization when only one parent is allergic, according to the type of allergy (respiratory, food, drug-related, or other) compared to a control group (no allergy for both parents)
Sponsors and contacts
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