PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care

ConditionHeart Failure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age49+
SponsorUniversidade do Porto

About this trial

The goal of this clinical trial is to evaluate whether the use of NT-proBNP testing and point-of-care ultrasound (POCUS) can improve the diagnosis and management of heart failure in adults aged 50 years or older with suspected heart failure or cardiovascular risk factors in primary care settings.

The main questions it aims to answer are:

* Does the use of NT-proBNP and/or POCUS increase the rate of new heart failure diagnoses compared with standard care? * Does this approach support earlier initiation of guideline-directed medical therapy and improve patients' quality of life?

Researchers will compare standard care alone with standard care combined with NT-proBNP testing, POCUS, or both, to assess their impact on diagnosis and management of heart failure.

Participants will:

* Be randomly assigned to one of four groups (standard care, NT-proBNP, POCUS, or both). * Undergo clinical evaluation for heart failure according to their assigned group. * Be followed for 12 months with periodic assessments of quality of life and treatment adherence.

Eligibility criteria

Qualifiers

Adults aged ≥50 years

Suspected heart failure (based on signs and/or symptoms) OR

Diabetes mellitus

Arterial hypertension

Disqualifiers

Known heart failure under active hospital-based follow-up

Terminal illness or life expectancy <1 year

Severe comorbid conditions limiting participation or follow-up

Inability to provide informed consent

Trial design

Treatments tested in this trial

  • NT-proBNP testing
  • Cardiac Point-of-Care Ultrasound (POCUS)
  • standard of care

Treatment groups

160 Participants
are divided into 4 treatment groups

Sponsors and collaborators