The ProActIF-01 trial aims to assess the feasibility of a supervised 8-week combined APA and nutrition individualized program, in advanced digestive cancer patients.
Signed and dated informed consent.
Age ≥ 18 years (no superior limit), men and women.
First-line treatment (chemotherapy and/or immunotherapy) for advanced disease (previous adjuvant therapy allowed).
Histologically confirmed adenocarcinoma or squamous cell carcinoma of digestive tract (colorectal, esogastric, pancreas, biliary tract).
Neuroendocrine carcinoma histology.
Any medical (including psychiatric, musculoskeletal, or neurological) condition contra-indicating exercise practice.
Nonfunctional gastrointestinal tract compromising oral/enteral feeding. Note: gastrointestinal tract obstruction is allowed if the tumor can be bypassed or stented (e.g. esophageal cancer with gastric tube-stoma or esophageal stent).
Participation to another physical activity or nutritional structured intervention program (in the first two months).