Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients

ConditionHalitoses

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-30

SponsorSara M Almshhadany

About this trial

This study aims to determine the effect of probiotics and Zn/CHx mouthwashes on plaque accumulation and halitosis in fixed orthodontic patients.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

good medical health

no systematic disease

non consuming drugs known to influence salivary flow, halitosis, or oral microbiota

Disqualifiers

alcohol drinking

smokers, pregnant and lactating womens

allergy or intolerance to corticosteroid treatment, antibiotic, antimicrobial mouth rinses, oral spray or tongue scraper, anti-inflammatory drugs or probiotics.

Trial design

Design model

Sequential

Treatments tested in this trial

Probiotic (L. brevis CD2 lozenges)
Other intervention
Probiotic :composed of powerful strain of s.salivarius that preserve innate immune system of the main entry point of the body by taken on a regular basis and establish colonization of the throat and mouth which provide clinical care and support of nose, ear, mouth and throat health and provide fresh breath.
Zinc chlorhexidine mouth wash
Behavioral
Zinc chlorhexidine mouth wash (Zn/CHX) composed of CHX concentrated 0.025% with Zinc acetate 0.3 %, the low concentration of CHX to maintain optimal efficacy with lower incidence of side effects. Zn /CHX was chosen as the active control due to the fact the mixture of Zn salts with low concentration of CHX have shown superior and sustained intra-oral efficacy in managing intra oral halitosis in randomized clinical tria

Treatment groups

60 Participants

are divided into 2 treatment groups

Group A: halitosisOther 2 interventions

Group B: Plaque accumulationOther 2 interventions

Trial outcomes

Primary outcomes

Plaque accumulation

plaque build up on bracket surfaces was evaluated by using modified bonded bracket index ( mbb index), Each tooth was divided into four areas (incisal, distal, mesial, gingival). Plaque accumulation was classified into the following assessment grades: grade 0-no plaque, grade 1-plaque covered ≤ 1/3 of the tooth surface, grade 2-plaque covered ≤ 2/3 of the tooth surface, grade 3-plaque covered \> 2/3 of the tooth surface. Plaque index (%)= Total of plaque values/ Number of surfaces/ Highest graduation score × 100.

Time frame

4 month

Halitosis

subjective assessment of halitosis determined by using organoleptic score (OLS) 0 No perceivable odor 1. Weakly perceivable odor 2. Perceivable odor 3. Moderate odor 4. Strong odor 5. Extremely strong odor

Time frame

4 month

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sara M Almshhadany

Lead sponsor

University of Baghdad

Sponsor institution

Source ClinicalTrials.gov

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