This study aims to investigate various aspects of patients with chronic respiratory diseases undergoing pulmonary rehabilitation supplemented with probiotics. The focus will be on clinical physiological responses, functional performance, respiratory status assessments, nutritional status evaluations, body composition analyses, and biochemical blood parameters, with a primary emphasis on the anti-inflammatory response.
Willing to sign a written informed consent form.
Diagnosed with pre-COPD or COPD stage I-IV according to the 2023 GOLD guidelines.
Undergoing pulmonary rehabilitation therapy for more than three months.
Under 18 years old.
Diagnosed with neuromuscular diseases.
Experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months.
Unable to cooperate with cardiopulmonary exercise testing.
Parallel
probiotic supplementation intervention
Other interventionprobiotic supplementation will be administered, while participants continue undergoing routine pulmonary rehabilitation therapy
standard pulmonnary rehabilitation
Other interventionundergo routine pulmonary rehabilitation without probiotics intervention
interleukin-6
inflammation evaluation
indirect calorimetry
nutrition status
body composition analysis
nutrition status
heart rate
physiological parameters
saturation
physiological parameters
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