About this trial
The aim of this study is to evaluate the role of procalcitonin in bronchoalveolar lavage as a biomarker for assessment of severity of non-CF bronchiectasis in children in correlation with other markers (functional and radiological severity )
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Children of both sex
Children aged from 6-17 years old.
Documented diagnosis of non-CF bronchiectasis by confirmed bronchiectasis findings using high-resolution computed tomographic (HRCT) lung scanning, and clinical symptoms consistent with bronchiectasis with a negative sweat test
Disqualifiers
Age less than 6 years or more than 17 years.
Children Diagnosed with cystic fibrosis bronchiectasis with confirmed positive sweat chloride test(6).
If there was a history of a recent exacerbation during the previous month preceding the study.
Trial population
Children aged from 6 to 18 years diagnosed with Non-cystic fibrosis bronchiectasis
Trial design
Case-control
Cross-sectional
Treatments tested in this trial
procalcitonin
Diagnostic testlevel of procalcitonin in bronchoalveolar lavage
Treatment groups
Trial outcomes
Primary outcomes
procalcitonin level in bronchoalveolar lavage as a biomarker for assessment of severity of non-CF bronchiectasis in children
comparison between procalcitonin level in Bronchoalveolar lavage and other markers of severity of bronchiectasis
Locations
Sponsors and contacts
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