Productive Value of Sonographic Measurement of Optic Nerve in Transitional Multiple

ConditionRelapsing Remitting Multiple Sclerosis

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age15-50

SponsorAssiut University

About this trial

1.to evaluate the potential role of the optic nerve diameter ( OND determined by ultrasonography and and visual nerve function by visual evoked potential as a biomarker of early axonal loss and disability in patients with relapsing remitting multiple sclerosis (RRMS).

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

1. both sex

Age group from 15 to 50 yrs

Patient with RRMS without history of optic neuritis

Disqualifiers

History of previous optic neuritis

Medical illness of eye(e.g. diabetes and hypertension)

MS patient on fingolimod for 6 months or more

Relapsing or use of steroid in the past 3 months

Trial population

both sex and RRMS with out previous optic neuritis

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

sonography
Device
measurement of optic nerve in RRMS by sonography and visual evoked potential( VEP) as correlation of axonal affection in RRMS patient

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

optic nerve measurement and correlation with axonal affection in RRMS

measurement of optic nerve diameter and optic nerve sheath diameter (in millimeter) in predicting progression in RRMS (Relapsing remitting multiple sclerosis)

Time frame

baseline

Secondary outcomes

2.Correlation of ultrasonography and visual evoked potential (change in p100 latency) with physical disability and cognitive score and fatigue by Multiple Sclerosis Functional Composite

Correlation of ultrasonography and visual evoked potential (change in p100 latency) with physical disability and cognitive score and fatigue by Multiple Sclerosis Functional Composite The score is based on a combination of timed tests of walking, arm function, and cognitive ability An integrated Multiple Sclerosis Functional Composite (MSFC) score is calculated using z-scores

Time frame

Baseline

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: