Prognosis of Cirrhotic Patients Admitted to the General Intensive Care Unit Between 2014 and 2024: a Regional Retrospective Multicentre Cohort Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorCentre Hospitalier Universitaire de Besancon

About this trial

Ten years after our team's publication, practices have changed considerably in the management of severe cirrhotic patients. This study will analyse these practices in primary care hospitals and in a tertiary centre, and assess the impact of these changes on the prognosis of these patients.

The following hypotheses will be tested:

* Improvement in intensive care and overall prognosis compared with data from the literature prior to 2014 * Improved access to liver transplantation compared with the literature prior to 2014 * Improvement in intensive care unit practices (for example: application of recommendations published by learned societies concerning the intensive care unit management of patients with cirrhosis, access to comfort care, degree of clinical severity on admission to the intensive care unit, etc.). * Centre' effect: variability in the phenotype of patients admitted to intensive care depending on the technical facilities available and whether or not the hospital centre has access to TH.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Patients with cirrhosis admitted to intensive care between January 2014 and December 2024.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • observational study

    Other intervention

    This observational study aims to describe the clinical practices and the outcome of patients admitted in ICU.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

28-day survival

Time frame
28 days

Secondary outcomes

1

Phenotype of patients admitted to intensive care

Time frame
baseline
2

Overall survival

Time frame
through study completion
3

Survival without liver transplantation

Time frame
12 months
4

Proportion of patients listed for liver transplantation

Time frame
through study completion

Other outcomes

Sponsors and contacts

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