This study investigates the prognostic value of dynamic changes in Drainage Tumor DNA(dT-DNA) levels found in the peritoneal drainage fluid after radical prostatectomy. Prostate cancer is one of the most common cancers in men, and radical prostatectomy is a standard treatment. While PSA levels in the blood are commonly used as a marker for diagnosis, this study focuses on the significance of dT-DNA levels in the prognosis of prostate cancer. The findings may provide insights into improved post-surgical monitoring and more tailored therapeutic strategies for prostate cancer patients.
Prostate cancer patients treated with radical prostatectomy
1. Received neoadjuvant endocrine/chemotherapy before surgery;
2. Urine leakage after surgery (positive creatinine test of drainage fluid).
The study will include male patients diagnosed with prostate cancer who need radical prostatectomy. Participants must have a preoperative diagnosis confirmed by biopsy and imaging studies. Eligible patients will have an abdominal drainage system in place post-surgery for fluid collection.
Cohort
Prospective
Not listed
dT-DNA Levels in Drainage Fluid
Postoperative dT-DNA Levels in The Peritoneal Drainage Fluid
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