Promoting Adherence to Chemotherapy Handling Guidelines Among Oncology Nurses
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Cincinnati
About this trial
Chemotherapy exposure is a serious occupational hazard affecting oncology nurses. Oncology nurses' adherence to chemotherapy handling guidelines is essential to prevent their exposure to chemotherapy. The goal of this research is to develop, validate, and pilot test an intervention "Workplace program to Improve Safe Handling of hazardous drugs" (WISH), to promote adherence to chemotherapy handling guidelines among oncology nurses. The WISH intervention includes two components: an educational component and debriefing sessions on chemotherapy exposure incidents. First, the research team will use a mixed-methods approach to develop an online educational component on chemotherapy safety, establish the content validity of the educational content based on experts' evaluation, and establish the face validity of the educational content by conducting three qualitative focus group with oncology nurses (n=4-6 nurses per group) or individual interviews. Next, the research team will test the feasibility and acceptability of the intervention using a pilot randomized controlled trial with two groups of oncology nurses, an intervention group (n= 30) and a control group (n=30). We will obtain quantitative and qualitative measures of the intervention feasibility and acceptability. The output is an intervention program targeted to train nurses on safe chemotherapy handling guidelines. Findings will be disseminated through peer-reviewed publications and presentations. The intermediate outcome is the adoption of the intervention program by healthcare institutions to train nurses on chemotherapy handling guidelines. The end outcome is promoting adherence to chemotherapy handling guidelines among oncology nurses.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
being at least 18 years old
able to read and speak English
working as an oncology nurse for at least 3 months
handling chemotherapy drugs at work
Disqualifiers
None
Trial design
Design model
Parallel
Treatments tested in this trial
The Workplace program to Improve the Safe Handling of hazardous drugs (WISH)
BehavioralThe WISH intervention is targeted to promote the adherence to chemotherapy handling guidelines among oncology nurses. The WISH intervention will include two components 1) an individualized online educational component on chemotherapy exposure and the safe handling guidelines with incorporating novel instructional technology tools and 2) debriefing sessions on the incidents of chemotherapy exposure.
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: WISH Intervention GroupExperimental treatment 1 intervention
Group B: Control GroupNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Nurses' adherence to chemotherapy handling guidelines
This variable will be measured using Hazardous Drug Handling Questionnaire. The scores reflect the percentage of time nurses adhere to chemotherapy handling guidelines and range between 0%-100%. A higher score indicates greater adherence to chemotherapy handling guidelines.
Time frame
Baseline, 6 weeks after the intervention, and 12 weeks after the interventionSecondary outcomes
1
Nurses' health beliefs regarding chemotherapy exposure
This variable will be measured using the health beliefs subscales in the Oncology Nurses Health Behaviors Determinants Scale. These subscales are: 1. Perceived Threat Subscale: range of scores is 5-25, a higher score indicates greater perceived threat of chemotherapy exposure. 2. Perceived Benefit Subscale: range of scores is 3 -15, a higher score indicates greater perceived benefits of adherence to chemotherapy handling guidelines. 3. Perceived Barriers Subscale: range of scores is 5-25, a higher score indicates greater perceived barriers of adherence to chemotherapy handling guidelines. 4. Perceived Self-Efficacy Subscale: range of scores is 6-30, a higher score indicates greater perceived self-confidence to adhere to chemotherapy handling guidelines.
Time frame
Baseline, 6 weeks after the intervention, and 12 weeks after the intervention2
Knowledge on chemotherapy safety
This variable will be measured using Chemotherapy Safety Knowledge questionnaire. This questionnaire will be developed by the study investigators; development is in progress.
Time frame
Baseline, 6 weeks after the intervention, and 12 weeks after the interventionOther outcomes
1
Study feasibility
Study feasibility will be measured in terms of the response rate (percent of nurses who responded relative to the number of potential participants who were reached), retention rates (percent of nurse participants who complete the posttests), the time required to reach the target sample size, and the engagement rate (the percent of actual interactions with participants relative to the planned number of interactions).
Time frame
Baseline, 6 weeks after the intervention, and 12 weeks after the intervention2
Intervention acceptability
Acceptability will be measured using Acceptability of Intervention Measure (score range is 4-20) and adapted measures of ease of use (score range is 3-15), usefulness (score range is 4-20), and satisfaction with the study experience (score range is 2-10) with an open-ended comment question. Higher scores indicate more positive acceptability of intervention.
Time frame
6 weeks after the intervention, and 12 weeks after the interventionSponsors and contacts
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University of Cincinnati
Lead sponsor
National Institute for Occupational Safety and Health (NIOSH/CDC)
Collaborator
Source ClinicalTrials.gov
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