About this trial
Self-medication has traditionally been defined as the consumption of medicines, herbs, and home remedies on one's own initiative or on the advice of another person, without consulting a doctor. In Spain, the consumption of non-prescription drugs is quite widespread among young people, since more than half of them have used medications without a medical prescription in the last year.
This high prevalence of self-medication among Spanish youth seems to be driven by various factors that encourage this practice. These include the increase in over-the-counter medications, delays in obtaining appointments at health centers, the influence of common family self-care practices, and the population's greater knowledge of and interest in health-related issues.
Inappropriate use of medications constitutes a public health problem and can cause significant risks to users' health, such as adverse reactions, drug resistance, and complications in diagnosing diseases, since it can lead to the masking of symptoms, as well as an increase in morbidity.
However, not all self-medication practices are harmful. Responsible self-medication refers to the use of over-the-counter medications (without a prescription) to treat common and mild symptoms (e.g., fever, mild pain, colds) for a reasonable period of time (two to three days, after which a doctor should be consulted if no improvement occurs). The benefits of responsible self-medication include convenience for the patient, reinforcement of personal autonomy through self-care, reduction of healthcare professionals' workload, and decreased costs to the healthcare system. In this regard, responsible self-medication not only provides individual and collective benefits but also promotes the development of personal autonomy, a key factor influencing young people's tendency to self-medicate. Attitudes toward autonomous medication use in young people are influenced by individual variables such as emotional regulation, family habits, peer influence, quality of life, and the use of other substances.
Given that these factors-greater access to medications, delays in healthcare access, family self-care practices, and individual psychosocial characteristics-appear to drive self-medication behaviors among youth, it is hypothesized that an educational intervention developed with the support of artificial intelligence, and focused on the responsible and safe use of medications, will improve young people's knowledge and attitudes toward self-medication. By targeting both knowledge and attitudes, the intervention aims to strengthen responsible practices while fostering autonomy and informed decision-making in medication use.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Inclusion criteria will include being a student at secondary education institutions, vocational training programs, or undergraduate degree programs in the province of Granada, and being between 15 and 24 years of age.
Disqualifiers
Exclusion criteria will include: lack of informed consent from the participant or their legal guardians in the case of minors, and the presence of barriers that prevent proper understanding of the questionnaires and activities to be carried out (e.g., language barriers, intellectual disability, etc.).
Trial design
Parallel
Treatments tested in this trial
Educational intervention
BehavioralThe intervention will consist of a structured educational program focused on the appropriate use of medications and the prevention of errors associated with self-medication.
Treatment groups
Trial outcomes
Primary outcomes
Risk Self-Medication Questionnaire focused on Health Literacy (QAR-LS)
The Risk Self-Medication Questionnaire focused on Health Literacy (QAR-LS) provides scores ranging from 35 to 175 points, where higher scores indicate a greater risk related to inadequate or unsafe self-medication practices.
Secondary outcomes
Health-related quality of life (Kidscreen-27)
The KIDSCREEN-27 (Screening for Health-Related Quality of Life in Children and Adolescents, 27-item version) consists of 27 items covering five dimensions: physical well-being, psychological well-being, autonomy and parent relations, social support and peers, and school environment. When summed, total raw scores may range from 27 to 135, although interpretation is typically based on dimension scores or standardized T-scores. Higher scores reflect better health-related quality of life.
Problem-focused coping styles (COPE-28)
The COPE-28 (Coping Orientation to Problems Experienced, 28-item version) consists of 28 items rated on a 4-point Likert scale. When summed, total scores range from 28 to 112, although interpretation is typically based on its subscales. Higher scores indicate greater use of the coping strategies assessed. The instrument includes 14 two-item subscales measuring specific coping responses, such as active coping, planning, seeking emotional or instrumental support, positive reframing, acceptance, humor, religion, self-distraction, denial, venting, substance use, behavioral disengagement, and self-blame. These can be grouped into broader domains (e.g., problem-focused, emotion-focused, dysfunctional coping).
Sponsors and contacts
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Universidad de Granada
Lead sponsor
Ministerio de Ciencia e Innovación, Spain
Collaborator