Propofol vs Sevoflurane in Cardiac Surgery
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSaint-Joseph University
About this trial
The hypothesis of our study: presence of a relationship between the type of anesthesia and complications after cardiac surgery. The aim is to assess the benefit of using intravenous or inhaled anesthesia on the patients\' stay and its complications.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
all patients above 18 yeras old that will undergo a cardiac surgery
Disqualifiers
below 18 yeras old
Trial design
Design model
Parallel
Treatments tested in this trial
sedation using propofol
DrugThe different complications studied will be for example respiratory, neurologic and cardiac based on several clinical and biological parameters.
sedation using sevoflurane
DrugThe differents complications studied will be for example respiratory, neurologic and cardiac based on severl clinical and biological parameters.
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: sedation using propofolPlacebo comparator 1 intervention
Group B: sedation using sevofluraneActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
determine the relationship between myocardial protection and type of anesthesia
troponin T dosage
Time frame
48 hours after the surgerySecondary outcomes
1
Association between the type of anesthesia and the speed of awakening
time taken to respond to simple commands, time elapsed to resume spontaneous ventilation
Time frame
48 hours after the surgery2
Association between the length of stay in intensive care and the type of anesthesia
duration of mechanical ventilation,
Time frame
72 hours after the surgery3
Determine a relationship between the type of anesthesia and the hemodynamic profile
measure cardiac output, vascular and pulmonary resistance, need for vasoamines
Time frame
48 hours after the surgery4
Association between the type of anesthesia and pulmonary complications
pulmonary complications: atelectasis, pneumonia, use of mechanical ventilation
Time frame
72 hours after the surgeryLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: