Health TrialsbyHealthPanel

Proprioceptive Deficits in Degenerative Cervical Myelopathy

ConditionCervical Myelopathy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50+
SponsorThe University of Hong Kong

About this trial

Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control. DCM usually presents with body incoordination, hand clumsiness and gait disturbance associated with proprioceptive dysfunction that hinders the physical performance and functions. In this study, a non-invasive assessment protocol on proprioception will be developed for detecting subtle proprioceptive deficits at the early stage of disease through simple Physical Performance Tests for population older than 45. By adopting the physical performance tests as the diagnostic predictors of DCM, we aim to avoid the development of devastating consequences and disabilities.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Chinese

Aged 50 or above

With radiological evidence of degenerative cervical myelopathy, both symptomatic and asymptomatic

Nurick grade less than 3

Disqualifiers

Non-Chinese ethnicity

Aged under 50

without any radiological proof of cervical myelopathy

Active problems of tuberculosis spine, lumbar spinal diseases, and other problems causing pain or deformities over the limbs that may affect their balance and movement

Trial population

Radiologically confirmed with Degenerative Cervical Myelopathy

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Proprioceptive Functional Analysis System

    Other intervention

    Proprioceptive testing and Physical Performance Tests

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: (1) Degenerative Cervical Myelopathy1 intervention
Group B: (2) Healthy Controls1 intervention

Trial outcomes

Primary outcomes

1

Modified Japanese Orthopaedics Association Scoring System for Cervical Myelopathy (mJOA)

mJOA is a self-reported functional questionnaire on disease severity through assessing 4 domains: 1. Upper Limb Function 2. Lower Limb Function 3. Sensory Function 4. Bladder Function mJOA has a total score of 17 and it categories DCM patient into different severity as below: 1. Mild \>= 15 2. Moderate = 12-14 3. Severe \< 12

Time frame
15 years

Secondary outcomes

1

Proprioceptive Deficits - Speed Test

Proprioceptive deficits hinder the limb coordination, especially the fine finger dexterity, reciprocal walking and stepping. Thus, incoordination over the lower and upper limbs will then be resulted and which alters the speed and integrity of the performance in the Physical Performance Tests validated for DCM. In the physical performance tests, it has divided into 2 separate sections, the "Speed Test" will be recorded for in terms of the "Time required to complete" the standardized test process in seconds

Time frame
15 years
2

Proprioceptive Deficits - Time Limited Test

Time Limited Test of physical performance test will be assessed and data will be recorded in terms of "Total number of repetitions completed" within strictly fixed time frame

Time frame
15 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

The University of Hong Kong

Lead sponsor

Source ClinicalTrials.gov
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