Proprioceptive Fatigue Adaptation in Osteoarthritis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age45-65
SponsorKocaeli Sağlık ve Teknoloji Üniversitesi
About this trial
This study aims to investigate the effects of fatigue induced by isokinetic exercise on passive and active joint position sense in postmenopausal women diagnosed with knee osteoarthritis (gonarthrosis). A healthy control group matched for age and sex will also be included for comparative analysis. Participants will undergo proprioceptive assessments before and after an isokinetic fatigue protocol. We hypothesize that (1) fatigue will impair both passive and active joint position sense in patients with gonarthrosis, (2) active joint position sense will be more affected than passive sense, and (3) the deterioration in proprioception will be greater in the gonarthrosis group compared to healthy controls.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Female, aged 50-65
Postmenopausal
Grade 2-3 knee osteoarthritis (Kellgren-Lawrence Scale) for OA group
No lower extremity surgery in the last 6 months
Disqualifiers
Severe balance disorders or vestibular disease
Bilateral knee prosthesis or severe osteoporosis
Lower extremity musculoskeletal injury in the last 6 months
Trial design
Design model
Parallel
Treatments tested in this trial
Fatigue Protocol + Joint Position Sense Testing
Diagnostic testGroups will undergo an isokinetic fatigue protocol at 180°/s using a Biodex dynamometer. Passive and active joint position sense tests will be performed before and after fatigue.
Treatment groups
20 Participants
are divided into 2 treatment groupsGroup A: Healthy ControlActive comparator 1 intervention
Group B: Gonarthrosis GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Joint Position Sense
Passive Joint Position Sense Test: The knee joint will be passively moved to 45°, then returned to the starting position. The participant will be asked to perceive and replicate the same angle passively. The difference between the perceived and actual angles will be recorded. An isokinetic dynamometer will be used during this test. Active Joint Position Sense Test: With their eyes closed, participants will be asked to actively move their knee to 45° and then return to the starting position. They will then be asked to actively reproduce the same angle. The difference between the measured and target angles will be recorded. An isokinetic dynamometer will be used during this test.
Time frame
From enrollment to the end of intervention for 10 minutesLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Kocaeli Sağlık ve Teknoloji Üniversitesi
Lead sponsor
Inonu University
Collaborator
Source ClinicalTrials.gov
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