Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorVA Office of Research and Development

About this trial

The purpose of this study is to characterize proprioceptive sensations in the missing limb of upper limb amputees using nerve stimulation, and to develop advanced controllers for moving a prosthesis. Proprioceptive sensations are the sensations that tell individuals where their hand is in space, and if it is moving. The research team uses Functional Electrical Stimulation (FES), which involves applying small electric currents to the nerves. These signals are then transferred to the brain just like the information about the individual's intact hand used to be transferred to their brain. This study will test different placements for stimulation and determine which one(s) provide the individual with proprioceptive sensations. The investigators want to know what the participants feel and if the investigators can use proprioceptive sensation to give the participants information about limb movement and position.

Eligibility criteria

Qualifiers

Veteran

Unilateral upper limb amputation above or below the elbow with fully healed and healthy surgical sites

Viable peripheral nerve function in the residual nerves serving the limb

Volitional activity of the residual muscles in the amputated limb or actuating movement of the limb

Disqualifiers

Bilateral upper limb amputation, unless the amputation on the contralateral side only involves missing digits but does not qualify as a partial hand amputation

Inability to speak English

Medically unfit to undergo surgery

Pregnancy, or those who are of childbearing potential, unwilling to prevent pregnancy during the trial

Trial design

Treatments tested in this trial

  • Chronically Implanted Neural and Muscular Interface

Treatment groups

8 Participants
are divided into 1 treatment group