About this trial
To further explore the application prospects of integrated Traditional Chinese and Western medicine in chronic disease prevention and control and health management, this study intends to establish a large, prospective, integrated Traditional Chinese and Western medicine cohort in Hubei Province. This study will conduct long-term follow-up and multi-dimensional data collection to systematically reveal the associations between Traditional Chinese Medicine (TCM) constitution types and chronic diseases, the aging process, and multi-morbidity, thereby developing an integrated health management strategy with local characteristics. This study will fill the current gap in systematic evidence linking TCM constitutions to the prevalence of modern diseases, providing a solid demographic and biological foundation for the integrated development of Traditional Chinese and Western medicine. It will also contribute to meeting the needs for early disease warning, early intervention, and personalized care under the "Healthy China" strategic goal.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Targeting urban and rural residents across multiple regions in Hubei Province, this study plans to recruit 1 million participants. Standardized protocols will be employed for baseline questionnaire surveys, physical examinations, and biological sample collection.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Prospective Cohort of Integrated Traditional Chinese and Western Medicine in China
Incidence of major chronic diseases (coronary heart disease, stroke, diabetes, COPD, lung cancer, colorectal cancer, gastric cancer, liver cancer, and esophageal cancer)
Secondary outcomes
All-cause mortality
Time Frame: From baseline to 10-year follow-up Measurement Tool: Death registry linkage and hospital records Unit of Measure: Mortality rate per 1,000 person-years
Other outcomes
Cause-specific mortality (cardiovascular, cancer, respiratory, metabolic)
Time Frame: From baseline to 10-year follow-up Measurement Tool: Death registry and ICD-10 coded cause of death Unit of Measure: Mortality rate per 1,000 person-years
Prevalence and progression of multimorbidity (≥2 chronic conditions)
Time Frame: Baseline to 10-year follow-up Measurement Tool: Questionnaire survey and physician-adjudicated diagnosis using ICD-10 Unit of Measure: % of participants with multimorbidity
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Huazhong University of Science and Technology
Lead sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborator
Hubei College of Traditional Chinese Medicine
Collaborator
Hubei Hospital of Traditional Chinese Medicine
Collaborator
Hubei Provincial Center for Disease Control and Prevention
Collaborator
Wuhan Center for Disease Control and Prevention
Collaborator
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