prospective, cohort, longitudinal, multicenter, non-randomized study of patients with non-infectious posterior segment uveitis or panuveitis, with a group of control patients (scheduled for cataract or vitreoretinal surgery) and constitution of biological collection.
Adult patients (≥ 18 years);
Non-infectious uveitis;
Intermediate, posterior or panuveitis;
Systemic corticosteroids or periocular or intravitreal injections of corticosteroids;
Isolated anterior uveitis ;
Absence of inflammatory chorioretinal and/or inflammatory retinal vascular lesion;
Anterior chamber cell grade< 0.5+;
Vitreous haze grade <0.5+;
Parallel
care strategy
Diagnostic testUveitis patients: * Blood sample (20ml): Additional 20 ml blood sample during the first visit and potentially during follow-up (if necessary) for the purpose of the biological collection; * Ocular sample (aqueous humor, vitreous): if required by the clinical context for the needs of the biological collection; * Specific imaging: adaptive optics or Doppler holography, these procedures will be indicated on a case-by-case basis, at the investigator's discretion, and concern only patients with inflammatory vascular damage (5 to 10% of patients in the uveitis cohort); * Quality of Life NEI-VFQ 25: provided at the inclusion visit and at follow-up visits M3-V2, M12-V5 and M24-V7.
Imaging database development
To develop an imaging database of Non-Infectious Uveitis of the posterior segment (NIUPS) using multimodal imaging
Biological constitution
To Constitute a biological collection of ocular and blood samples of NIUPS patients and controls
medico economic costs estimation
To estimate the current costs of treatment by ensuring linkage of cohort patients to the national claims database
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Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Lead sponsor
Groupe Hospitalier Pitie-Salpetriere
Collaborator
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