Prospective Cohort Study of Neuromyelitis Optica Spectrum Disorders (NMOSD)
ConditionNMOSD
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorXiamen Hospital of Traditional Chinese Medicine
About this trial
This study aims to characterize sex hormone alterations and their potential clinical significance in NMOSD patients from Southern China through comprehensive hormonal profiling.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged 18 years or older, regardless of sex
Fulfilled the diagnostic criteria for Neuromyelitis Optica Spectrum Disorders as defined by the 2021 Chinese guidelines for the diagnosis and management of NMOSD
Seropositive for AQP4-IgG
Provided informed consent by the participant or their legal guardian
Disqualifiers
Diagnosis of other serious systemic diseases (e.g., malignancy)
Presence of severe psychiatric disorders that would preclude compliance with study procedures and/or follow-up assessments
History of infectious pathologies of the central nervous system
Those with severe liver and kidney function impairment or dysfunction of other vital organs
Trial population
The population of NMOSD patients in Southern China
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Sex hormone assay
Other interventionThis study will explore and validate the characteristics of sex hormone levels in MNMOSD
Sex hormone assay
Other interventionThis study will explore the comparison of sex hormone levels between a healthy control group and MNMOSD
Treatment groups
4,000 Participants
are divided into 2 treatment groupsGroup A: MNOSD patient group1 intervention
Group B: Healthy control group1 intervention
Trial outcomes
Primary outcomes
1
Variations in Serum Sex Hormones
Time frame
Baseline, 6 months, 12 months, 18 months, 24 months, 30 months, 36 months.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: