About this trial
Quantify the level of endocan in blood samples collected from patients with acute diverticulitis in the emergency department. Determine if endocan levels are correlated with the severity of diverticulitis according to the WSES classification. Assess whether patients requiring emergency surgical intervention have higher endocan values compared to others.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients who have signed informed consent
Patients who are affected by acute diverticulitis after clinical evaluation and imaging (i.e. u.s. or CeCT)
Disqualifiers
Immunosuppressed patients
Patients suffering chronic inflammatory diseases
Patients with concomitant malignancy, cardiac, renal and haepatic failure
History of major vascular surgery (aneurysmectomy)
Trial population
Patients affected by acute diverticulitis in the emergency department
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Endocan serum level at admission
To evaluate the correlation between blood concentration of endocan and severity of diverticulitis
Secondary outcomes
Predictive value of endocan in determining which patients need emergency surgery
Concentration of endocan in grade 3-4 WSES compared to grade1-2
Prognostic value of endocan in determining the risk of recurrent diveritculitis
Concentration of endocan in patient who develop a recurrence after 1 year follow-up
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: