About this trial
we aim :
* To evaluate how frailty influences acute management decisions (invasive vs conservative strategy) in ACS patients and whether it independently affects short-term outcomes. * To determine whether adding frailty assessment to existing ACS risk prediction models improves the prediction of 30-day mortality and major adverse cardiovascular events (MACE) in elderly ACS patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Elderly: Age ≥65 years .
STEMI/NSTEMI (ESC/ACC criteria)
Presentation <24h of symptom onset
Disqualifiers
Terminal illness (life expectancy <1 month)
Severe dementia precluding assessment
Declined consent
Trial population
The study population consists of patients aged ≥65 years presenting with STEMI or NSTEMI within 24 hours of symptom onset, excluding those with terminal illness, severe dementia, or refusal of consent.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
30-day Major Adverse Cardiovascular Events (MACE)
Composite outcome including cardiovascular death, non-fatal myocardial infarction, stroke, or urgent revascularization, stratified by frailty status.
Secondary outcomes
All-cause mortality
Mortality occurring during index hospitalization
Acute Kidney Injury (AKI)
AKI defined according to KDIGO criteria (increase in serum creatinine ≥0.3 mg/dL within 48 hours or ≥1.5 times baseline within 7 days).
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: