Prospective Observational Cohort Study on Impact of Frailty on Risk Prediction, Treatment Strategies, and Short-Term Outcomes in Patients With Acute Coronary Syndrome

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorAssiut University

About this trial

we aim :

* To evaluate how frailty influences acute management decisions (invasive vs conservative strategy) in ACS patients and whether it independently affects short-term outcomes. * To determine whether adding frailty assessment to existing ACS risk prediction models improves the prediction of 30-day mortality and major adverse cardiovascular events (MACE) in elderly ACS patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Elderly: Age ≥65 years .

STEMI/NSTEMI (ESC/ACC criteria)

Presentation <24h of symptom onset

Disqualifiers

Terminal illness (life expectancy <1 month)

Severe dementia precluding assessment

Declined consent

Trial population

The study population consists of patients aged ≥65 years presenting with STEMI or NSTEMI within 24 hours of symptom onset, excluding those with terminal illness, severe dementia, or refusal of consent.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

30-day Major Adverse Cardiovascular Events (MACE)

Composite outcome including cardiovascular death, non-fatal myocardial infarction, stroke, or urgent revascularization, stratified by frailty status.

Time frame
30 days after index admission

Secondary outcomes

1

All-cause mortality

Mortality occurring during index hospitalization

Time frame
30 days after index admission
2

Acute Kidney Injury (AKI)

AKI defined according to KDIGO criteria (increase in serum creatinine ≥0.3 mg/dL within 48 hours or ≥1.5 times baseline within 7 days).

Time frame
30 days after index admission

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: