To explore associations with demographics/clinical factors; assess trajectories via annual follow-up; evaluate healthcare utilization and barriers; oversample \>10-year survivors.
Age ≥40 years with no upper age restriction, provided performance status permits procedural candidacy
Symptomatic mild-to-severe knee osteoarthritis (Kellgren-Lawrence grade 2-4) on radiographs within 6 months of enrollment
Chronic knee pain (NRS ≥4/10) for ≥3 months despite conservative treatment including steroid injections, physical therapy, and/or analgesic medications
Inadequate candidate for or refusal of surgical intervention (e.g., total knee arthroplasty) due to cancer-related comorbidities, ongoing treatment, or participants preference
Active joint infection or suspected septic arthritis
Life expectancy <6 months
Prior knee arthroplasty in the index knee
Coagulopathy or contraindications to angiography
UT MD Anderson Cancer Center
Cohort
Prospective
SOC (Standard of care)
Other interventionPatients scheduled for standard of care
Numeric Rating Scale Questionnaire
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