Observational study to evaluate longitudinal quality of life according to standardized EORTC questionaires as well as functional outcome, oncological outcome and toxicity in patients treated with definitive chemoradiation for anal cancer
histologically proven anal cancer without distant metastases
indication for definitive chemoradiation therapy based on multidisciplinary evaluation
age >=18 years
written informed consent
age < 18 years
prior systemic therapy with regard to anal cancer
distant metastases
second malignancy
see eligibility criteria
Cohort
Prospective
EORTC QLQ C30
Other interventionstandardized questionaire
EORTC QLQ CR29
Other interventionstandardized questionaire
Qol (EORTC QLQC30) absolute values and change over time
Quality of life measured by EORTC questionaire QLQC30 in absolute values at different time points and change over time
Qol (EORTC QLQCR29) absolute values and change over time
Quality of life measured by EORTC questionaire QLQCR29 in absolute values at different time points and change over time
local control
absence of disease progression inside the target volume of radiation therapy
distant control
absence of disease progression outside the target volume of radiation therapy
freedom from treatment failure
absence of disease progression inside or outside the target volume of radiation therapy
overall survival
absence of death from any cause
Click on the lead sponsor to view all of their trials.
