About this trial
To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g. death, non-communicable disease development) across a range of socioeconomic and health resource settings. Additional components of this study will examine genetic factors for non-communicable diseases. This will be examined both through a cross sectional component, and prospectively (cohort component).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
consenting adults between 35-70 years of age
Disqualifiers
none
Trial population
Adults aged 35 to 70 years from communities in low-, middle-, and high-income regions of the world representing various levels of development and encompassing great sociocultural diversity.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
incident cardiovascular disease
cardiovascular death, stroke, myocardial infarction, heart failure
Secondary outcomes
incident cancer
total and cause specific cancers
Incident COPD
development of COPD
Incident Asthma
development of asthma
Pneumonia
hospitalization for pneumonia
Sponsors and contacts
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Population Health Research Institute
Lead sponsor
Canadian Institutes of Health Research (CIHR)
Collaborator
Heart and Stroke Foundation of Ontario
Collaborator