The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery. Therefore, this research aims to better understand protein expression in patients indicated for surgical treatment of obesity, evaluating the pre-operative and post-operative status. The objective of this research is to better understand protein expression in patients indicated for surgical treatment of obesity, evaluating the pre-operative and post-surgery status.
patients over 18 years of age with a BMI above 35 kg/m² associated with comorbidity or BMI above 40 kg/m² without comorbidities,
Patients with a previous history of cancer;
Underage patients
Patients with other diseases predisposing to the development of cancer: cirrhosis, ulcerative colitis, Barrett's esophagus, etc.
Patients who have previously undergone bariatric surgery;
Single group
bariatric surgery
Procedure/Surgerysleeve gastrectomy
7
Treatment groupsSee each treatment group below.
Number of patients with reduced initially upregulated oncogenic proteins
reduction of proteins potentially involved in oncogenic metabolic pathways, initially upregulated in the context of obesity
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