About this trial
Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD. It is supposed to be symmetrical between the 2 lungs with the same PEEPi. EIT can measure the distribution of tidal ventilation and interlung lung insufflation delay on the impedance time curve of each lung. Moreover, it is possible in intubated COPD patients to assess one lung PEEPi during low flow insufflation with pressure-EIT monitoring.
This study aims to measure interlungs insufflation delay under mechanical ventilation in COPD patients
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients hospitalized in the ICU and who suffered moderate or severe COP (Gold 3 and 4)), with respiratory acidosis under NIV or intubated, and equipped with EIT over the age of 18.
Disqualifiers
Broncho-pleural leaks
Pregnant or breastfeeding woman.
Guardianship or curatorship
Deprived of liberty
Trial population
Patients with Acute Respiratory Distress Syndrom in prone position
Trial design
Other
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Assessing inter-lungs insufflation delay under NIV or invasive mechanical ventilation on the impedance-time curves without PEEP.
Secondary outcomes
Assessing inter-lungs insufflation delay under NIV or invasive mechanical ventilation on the impedance-time curves with PEEP.
Comparison of End Expiratory Lung Impedance with or without PEEP
Post treatment analysis of EIT low flow PV curves in intubated sedated patients, measurement of each lung PEEPi
Sponsors and contacts
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