Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier de la côte Basque

About this trial

Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD. It is supposed to be symmetrical between the 2 lungs with the same PEEPi. EIT can measure the distribution of tidal ventilation and interlung lung insufflation delay on the impedance time curve of each lung. Moreover, it is possible in intubated COPD patients to assess one lung PEEPi during low flow insufflation with pressure-EIT monitoring.

This study aims to measure interlungs insufflation delay under mechanical ventilation in COPD patients

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients hospitalized in the ICU and who suffered moderate or severe COP (Gold 3 and 4)), with respiratory acidosis under NIV or intubated, and equipped with EIT over the age of 18.

Disqualifiers

Broncho-pleural leaks

Pregnant or breastfeeding woman.

Guardianship or curatorship

Deprived of liberty

Trial population

Patients with Acute Respiratory Distress Syndrom in prone position

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Assessing inter-lungs insufflation delay under NIV or invasive mechanical ventilation on the impedance-time curves without PEEP.

Time frame
Only 1 visit

Secondary outcomes

1

Assessing inter-lungs insufflation delay under NIV or invasive mechanical ventilation on the impedance-time curves with PEEP.

Time frame
Only 1 visit
2

Comparison of End Expiratory Lung Impedance with or without PEEP

Time frame
Only 1 visit
3

Post treatment analysis of EIT low flow PV curves in intubated sedated patients, measurement of each lung PEEPi

Time frame
Only 1 visit

Other outcomes

Sponsors and contacts

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