Health TrialsbyHealthPanel

PUMCH Dementia Longitudinal Cohort Study

ConditionsDementiaDementia, VascularDementia With Lewy BodiesDementia, MixedDementia AlzheimersDementia FrontalDementia, Mild
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorPeking Union Medical College Hospital

About this trial

The PUMCH Dementia Cohort is a hospital-based, observational study of Chinese elderly with cognitive impairment.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Neurodegenerative dementia diagnosis based on 2011 NIA-AA criteria of Dementia

Fixed care giver and can follow up regularly

Disqualifiers

Not demented, including MCI

Systemic severe diseases and severe vision or hearing problem effecting follow up and neuropsychological evaluation

Without fixed care giver

Reject informed consent

Trial population

We included age stratified dementia (early onset, late onset, oldest old) , including AD, FTD,VaD, DLB and mixed dementia. Also we include cognitive normal controls.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

20,000 Participants
are grouped into 4 trial groups
Group A: Early onset dementia
Group B: Late onset dementia
Group C: Oldest old dementia
Group D: Cognitive normal control

Trial outcomes

Primary outcomes

1

The incidence of dementia

Through follow up of cognitive normal control ,to find the incidence of dementia in PUMCH cohort

Time frame
Through study completion,an average of 10-20 years
2

The relationship between lifestyles, stress (stressful events and their degree) and dementia

Analysis of the relationship between lifestyles, stress and progression of dementia. Discover lifestyle factors (such as diet, residential environment, physical activity, hobbies, and sleep) and stress (stressful events and their degree) by using a questionnaire designed by PUMCH

Time frame
Through study completion,an average of 10 years
3

Risk factors for dementia

Collect the risk factors in normal control and analysis the relationship after diagnosis of dementia

Time frame
Through study completion,an average of 10-20 years
4

Cognitive decline

Use a systematic neuropsychological battery designed by PUMCH

Time frame
Through study completion,an average of 10-20 years

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Peking Union Medical College Hospital

Lead sponsor

Source ClinicalTrials.gov
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