About this trial
The QUAD-HF registry is an observational study that would enroll patients in the United Kingdom, who have been newly diagnosed with heart failure and a left ventricular ejection fraction \<50%. We plan to assess clinical outcomes in these patients, such as hospitalization and death, in relation to their diagnosis, implementation of guidelines and type of treatments these patients have received.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age >18 years
Newly diagnosed Heart Failure with a Left Ventricular Ejection Fraction <50% (≤12 Weeks prior to enrolment).
Able and willing to consent.
Disqualifiers
LVEF 50% or more at time of diagnosis
Palliative care
Unable or unwilling to give consent
Trial population
Eligible participants would include adult patients (\>18 years) attending HF clinics in hospital or community settings or those hospitalized for the management of Acute Decompensated Heart failure (ADHF), who have been newly diagnosed HF with a left ventricular ejection fraction of \<50%, no more than 12 weeks prior. Patients would be excluded if they have had a previous diagnosis of heart failure, are on a palliative care pathway or are unable or unwilling to consent.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Cardiovascular Mortality or Hospitalization for Heart Failure
Death due to cardiac causes or hospitalization due to worsening heart failure symptoms
Secondary outcomes
All-cause mortality
Death due to any cause
Cardiovascular Mortality
Death due to cardiac causes
Hospitalization for Heart Failure
Hospitalization due to worsening heart failure symptoms
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Mid and South Essex NHS Foundation Trust
Lead sponsor
Anglia Ruskin University
Collaborator
British Society for Heart Failure
Collaborator