Quality of Pediatric Resuscitation in a Multicenter Collaborative
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-18
SponsorChildren's Hospital of Philadelphia
About this trial
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests.
The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patient received chest compressions for at least 1 minute
Patient between gestational age ≥37 weeks and 18 years of age
Disqualifiers
Patient on veno-arterial extracorporeal membrane oxygenation (ECMO) therapy at beginning of CPR event
Trial population
Data will be collected from pediatric cardiac arrest events as part of standard clinical operations.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
7,000 Participants
are grouped into 1 trial groupGroup A: Pediatric Cardiac Arrests
Trial outcomes
Primary outcomes
1
Aggregate score composed of American Heart Association (AHA) recommended depth, rate, and chest compression fraction during CPR
Primary outcome: "Guideline-compliant CPR" which will be determined by an aggregate score comprised of the following three components: depth, rate, and chest compression fraction. The three components will be analyzed in 30 and 60 second epochs. "Guideline-compliant CPR" requires that each component meet the following criteria: 1) Age-determined American Heart Association (AHA) guideline recommended depth; 2) rate ≥ 90 and ≤ 120 CC/min; and 3) CC Fraction ≥ 0.80. Depth, rate, and CC Fraction will be calculated for each epoch and an aggregate score will be assigned. The primary analysis will be performed on that total score.
Time frame
10 YearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Children's Hospital of Philadelphia
Lead sponsor
Zoll Medical Corporation
Collaborator
Source ClinicalTrials.gov