Quantitative MRI for Myelofibrosis

ConditionMyelofibrosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorUniversity of Michigan Rogel Cancer Center

About this trial

This study is for the development and validation of functional magnetic resonance imaging (MRI) parameters as biomarkers for analyzing extent of disease and quantifying response to treatment in patients with myelofibrosis.

Eligibility criteria

Qualifiers

Male /female subjects over the age of 18

Diagnosis of primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis.

No contraindications to MRI

Able to undergo MRI without anesthesia

Disqualifiers

Patients with pacemakers or other implanted magnetic devices that may malfunction or move because of the strong magnetic field inside the MRI room and scanner.

Any prior adverse event associated with MRI that is not related to injection of contrast agents or other medicines.

Trial design

Treatments tested in this trial

  • T1 Weighted MRI (magnetic resonance imaging)

Treatment groups

192 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Michigan Rogel Cancer Center

Lead sponsor

Sanofi

Collaborator

National Cancer Institute (NCI)

Collaborator