About this trial
This is a prospective observational study to observe the diagnostic efficacy of a quantitative ultrasound assessment plan for pathological accumulation in the abdominal cavity space of critically ill patients, and to explore its correlation with patient clinical outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age > 18 years old;
Expected ICU stay ≥ 72 hours;
Meeting one of the diagnostic criteria for intra-abdominal infection: 1) Single organ infection (such as cholecystitis, appendicitis, diverticulitis, cholangitis, pancreatitis, salpingitis, etc.), which may be accompanied by or without peritonitis, even without perforation; 2) Peritonitis, classified as primary, secondary, or recurrent; 3) Intra-abdominal abscess.
Disqualifiers
Patients with wounds, redness, swelling, bleeding, or other conditions at the abdominal measurement points that prevent ultrasound assessment;
Patients with intra-abdominal gas accumulation that affects abdominal ultrasound imaging, making ultrasound quantitative scoring impossible;
Patients who have not undergone abdominal CT examination within 72 hours of ICU admission;
Patients who do not consent to participate in this study.
Trial population
Critically ill patients in the Department of Critical Care Medicine at Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Quantitative CT Scoring for Pathological Accumulations in the Abdominal Cavity Space
score range from 0-20, higher scores indicate a worse outcome
Quantitative Ultrasound Scoring for Pathological Accumulations in the Abdominal Cavity Space
score range from 0-20, higher scores indicate a worse outcome
Secondary outcomes
Time to initiate enteral nutrition
Time to initiate enteral nutrition after admission to ICU in hours
Intra-abdominal pressure
Intra-abdominal pressure in mmHg
C-reactive protein
C-reactive protein in mg/L
procalcitonin
procalcitonin in ng/L
Sponsors and contacts
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