About this trial
Knee osteoarthritis is one of the most common causes of chronic pain and disability worldwide, particularly in middle-aged and elderly populations. It is characterised by progressive cartilage degeneration, subchondral bone remodelling, and synovial inflammation.
There were many trails to provide pain relief by using systemic opioids or Non steroidal anti inflammatory drugs (with side effects such as peptic ulcer and hepatic, renal impairment)
Eligibility criteria
Qualifiers
American society of anesthesiologist's physical status class I, II- Body mass index (BMI): 18.5 - 29.9 kg/m2- Confirmation of knee OA on radiograph- Chronic knee pain ≥ 3 months.
Disqualifiers
History of clinically significant cardiac, hepatic, renal or neurological disease- Allergy to study medication- Coagulopathy- Infection at injection site
Trial design
Treatments tested in this trial
- Laser genicular nerve ablation
- Conventional radiofrequency genicular nerve ablation