About this trial
The aim of our study is to find the best imaging technique, alone or in combination, that can best predict a complete response (absence of tumour cells). It also seems important to identify blood markers able to predict which patients will benefit most from treatment, with a view to personalising them, or which patients will be most at risk of toxicities, particularly related to immunotherapy, with a view to personalising monitoring.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Signed informed consent
Patient with histologically proven TNBC
Indication for neo-adjuvant chemo-immunotherapy treatment
Age between 18 and 75
Disqualifiers
Pregnant or breast-feeding women
Contraindication to immunotherapy
Inflammatory breast cancer (T4d)
Metastatic patients
Trial design
Single group
Treatments tested in this trial
Imaging assessment
Other interventionThe patient will have four imaging exam : Ultrasound, angio/mammography, MRI and PET-scan
Treatment groups
Trial outcomes
Primary outcomes
concordance rate between quadrimodal radiological assessment (ultrasound, angiography/mammography, MRI, PET-CT) and histologically-obtained response following neoadjuvant chemo-immunotherapy in patients with triple-negative breast cancer (TNBC).
concordance of the response between radiological assessement and histological response
Sponsors and contacts
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