Rapid Non-Invasive Brain Stimulation for Hoarding Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorStanford University
About this trial
This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18-70 years
Primary diagnosis of hoarding disorder
Sufficient severity of hoarding symptoms
Willing and able to understand and complete consent and study procedures
Disqualifiers
Psychiatric or medical conditions or medications that make participation unsafe
Pregnant or nursing females
Previous exposure to TMS or ECT
History of any implanted device or psychosurgery
Trial design
Design model
Single group
Treatments tested in this trial
MagPro X100 by MagVenture
DeviceParticipants will receive 5 session per day of TBS for 6 days (30 sessions total). Six treatment days have to occur within a 2 week period. Each session will be comprised of 1800 pulses, using a MagVenture MagPro X100.
Treatment groups
10 Participants
are divided into 1 treatment groupGroup A: Theta-burst stimulation (TBS)Experimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Change in Compulsive Acquisition Scale (CAS)
The Compulsive Acquisition Scale (CAS) is an 18-item questionnaire that measures the extent to which individuals acquire and feel compelled to acquire possessions. The total score (sum of 18 items) ranges from 0 to 126. Total score higher than 48 shows significant difficulty with acquiring.
Time frame
Change from baseline to 3 weeks after treatment startsOther outcomes
1
Change in Hoarding Symptom Severity as Measured by Saving Inventory-Revised (SI-R)
The Saving Inventory-Revised scale (SI-R) is a 23-item questionnaire with 3 factor-analytically defined sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition. The total score (sum of 23 items) ranges from 0 to 92. Total score higher than 41 shows significant difficulty with clutter. For the acquisition subscale, items 2 (reverse score), 9, 11, 14, 16, 18 and 21 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with excessive acquisition. For the difficulty discarding subscale, items 4(reverse score), 6, 7, 13, 17, 19, 23 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with discarding. For the clutter subscale, items 1, 3, 5, 8, 10, 12, 15, 20, 22 are summed together. The subscale ranges from 0 to 36 and score greater than 15 indicates difficulty with accumulated clutter.
Time frame
Change from baseline to 3 weeks after treatment startsSponsors and contacts
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Source ClinicalTrials.gov