The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential risk factors for malignant transformation, and to evaluate the therapeutic effects and features to OLP drgus.
Clinical-histological diagnosis of Oral lichen planus
Patients who gave consensus to personal data treatment
Minimum 6 months follow-up
Patients who did not give consensus to personal data treatment
Oral lichenoid lesions
Patients with anamnesis of hematopoietic stem cells transplant
Patients with a OSCC at the first histological examination (i.e., namely: also OSCC patients with a OLP background were excluded)
A cohort of patients affected by oral lichen planus
Cohort
Retrospective
Not listed
Number of Oral Carcinomas
Number of cases that will be histologically diagnosed as Oral Carcinomas. This outcome will be expressed as a dichotomous variable (i.e., yes/no).
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