Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50+
SponsorChang Gung Memorial Hospital

About this trial

The goal of this observational study is to learn about the impact of sarcopenia (muscle loss) on the efficacy of regional nerve blocks and postoperative recovery in patients undergoing upper extremity surgery. The main questions it aims to answer are:

1. Does sarcopenia affect the onset time and success rate of peripheral nerve blocks? 2. How does sarcopenia influence postoperative pain control and opioid consumption compared to patients receiving pure general anesthesia?

Participants will undergo a preoperative muscle assessment, which includes a chair stand test and a brief ultrasound of the thigh muscle. Researchers will then observe and record their nerve block onset time (if applicable), postoperative pain scores, and recovery metrics during their hospital stay up to postoperative day 2.

Eligibility criteria

Qualifiers

Age>=50 years old

ASA I-III

Receiving upper limb surgery under general anesthesia

Disqualifiers

Severe cognitive impairment or inability to cooperate with pain and motor assessment

Pre-existing neuropathy of the musculocutaneous, median, radial or ulnar nerve

(for nerve block group) Contraindications to regional nerve blockade

Trial design

Treatments tested in this trial

  • sarcopenia
  • Non-sarcopenia
  • General Anesthesia
  • Nerve Block

Treatment groups

150 Participants
are divided into 3 treatment groups

Sponsors and collaborators