About this trial
Takotsubo syndrome is a condition which mimics acute myocardial infarction, and is diagnosed in 1.5% to 2.2% of patients referred to hospital with suspected acute coronary syndrome. It is also known as broken heart syndrome, takotsubo cardiomyopathy, stress cardiomyopathy and apical ballooning cardiomyopathy, among other names. The pathogenesis of this disorder is not well understood. Possible mechanisms include catecholamine excess, coronary artery spasm, microvascular dysfunction, among others. This is a multicenter, nation-wide, observational study of patients who were previously diagnosed with takotsubo syndrome. The investigators aim to use this registry to help plan and carry out further studies and to improve understanding of the pathophysiologic mechanisms of this syndrome. In addition participants will be followed for events, and to monitor quality of life and stress.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Physician diagnosis of takotsubo syndrome
Age>18 years
Disqualifiers
None
Trial population
Patients with history of takotsubo syndrome
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Major Adverse Cardiac Events
Medical record review and patient report of repeat takotsubo event, MI, heart failure, unstable angina, chest pain ER visit, cardiovascular death, stroke
Secondary outcomes
Quality of life assessed using the Patient Reported Outcome Measurement Information System (PROMIS-10) questionnaire
Measure of quality of life
Anxiety is assessed using the Hospital Anxiety and Depression Scale (HADS-A)
Measure of anxiety
Depression assessed using the Patient Health Questionnaire (PHQ-9)
Measure of depression
Perceived stress is measured using the Perceived Stress Scale (PSS-10)
Measure of perceived stress
Sponsors and contacts
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