Relationship Between Mouth Opening and Masseter Elasticity in Oral Cancer
ConditionOral Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-65
SponsorNational Taiwan University Hospital
About this trial
The study aims to assess the hardness of masticatory muscles in post-surgical oral cancer patients using strain elastography ultrasound, calculating the masseter elasticity index and exploring its association with maximum interincisal mouth opening. Furthermore, the study incorporates exercise training to analyze whether changes in masseter hardness can serve as an objective indicator for predicting the improvement of trismus.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Newly diagnosed oral cancer patients who are scheduled to receive cancer-related treatments (e.g., oral cancer surgery, radiotherapy, chemotherapy, or chemoradiotherapy).
Age between 20 and 65 years.
Disqualifiers
Could not communicate.
Had any disorder that could influence movement performance.
Trial population
A total of 10 patients, aged 20 to 65 years, are first diagnosed with oral cancer and underwent surgery and routine physical therapy within three months.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
ultrasonographic imaging
Diagnostic testmasseter muscle elasticity
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Masseter muscle elasticity
The masseter elasticity index is calculated as the ratio of the average elasticity of the masseter muscle to that of the isolation-coupling Pad (icPad).
Time frame
Pre-intervention, 8 weeks post-intervention2
Maximum interincisal mouth opening
Maximum interincisal mouth opening is measured using a mouth-opening ruler, placed at the edges of the upper and lower central incisors to determine the distance.
Time frame
Pre-intervention, 8 weeks post-interventionSponsors and contacts
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Source ClinicalTrials.gov