About this trial
This study aims to explore, in patients with chronic non-specific low back pain (cnsLBP), the relationships between lumbar muscle activity, structural and morphological characteristics of the paraspinal muscles, and movement strategies, during a functional, ecological task: walking. To do this, we will compare a group of cnsLBP patients with a group of asymptomatic subjects, combining several types of measurements taken at different walking intensities: spinal kinematics (movement strategies), electromyographic activity of the lumbar muscles, and structural parameters of the paraspinal muscles (stiffness and thickness). The objective is twofold: first, to identify any significant differences between cnsLBP patients and healthy subjects on these combined parameters; second, to explore the interactions between these three dimensions (muscle activity, muscle structure, movement strategy) in order to better understand their relationships with pain and with how CNSLBP functions during physical activity. This multidimensional, ecological approach could also help identify subgroups within the cnsLBP population, reflecting the clinical heterogeneity already documented in the literature. Ultimately, the expected results will contribute to a better understanding of the biomechanical and neuromuscular mechanisms involved during physical activity in these patients, and will provide objective elements to help individualize physical activity recommendations according to each patient's profile.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adult aged 18 to 65 years (inclusive)
Have freely given written informed consent
Present with pain located between the thoracolumbar junction and the inferior gluteal fold, with or without pain in one or both legs
This pain must have been present for more than 12 weeks, on a daily or near-daily basis (at least 4 days out of 7)
Disqualifiers
None
Trial design
Parallel
Treatments tested in this trial
Supervised Progressive Walking Test
Other interventionAfter a warm-up period on the treadmill, the test involves walking, starting at a speed of 3 km/h and increasing the speed by 0.5 km/h every 2 minutes, up to a maximum of 7 km/h. The speed of 7 km/h is a target speed and is not mandatory.
Treatment groups
Trial outcomes
Primary outcomes
Change in muscle stiffness of the erector spinae and multifidus muscles between rest and after physical activity
Change in muscle stiffness, measured by shear modulus using shear-wave elastography, of the erector spinae and multifidus muscles, between rest and after physical activity.
Secondary outcomes
Ultrasound morphological measurements
Measurement of the cross-sectional area and thickness-as determined by ultrasound-of the erector spinae and multifidus muscles at rest.
Electromyographic activity
Lumbar muscle activations during three-dimensional lumbar movements and while walking
Kinematics
The kinematics of the lumbopelvic-femoral complex (segmental velocity and acceleration, joint angles) during three-dimensional movements and while walking.
General data
Age, sex, height, weight, body mass index, and socioeconomic status are recorded.
Sponsors and contacts
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