About this trial
The International Olympic Committee recently published its consensus statement on relative energy deficiency syndrome (REDs) in sport which was followed by a similar version for dance by clinicians and researchers in dance. REDs is a complex multisystem syndrome with low energy availability as its foundation. Dancers and gymnasts, particularly in ballet, have long been reported to have body weight issues with an increase prevalence of eating disorders which has been associated with early onset osteoporosis. Combat sports have a similar issue, with athletes needing to "make weight" to compete in their ideal weight category that has lead to similar eating disorder and associated issues to dance. Currently there are no data on REDs prevalence in dance, gymnastics or combat sports and therefore understanding the underlying prevalence of REDs in both these populations will provide important information for both clinicians and coaches to help develop a safe and healthy environment for their dancers and athletes to compete/perform and to be able to retire from sport/dance without an increased risk of osteoporosis. In a few sports and dance genres, some participants might be more prone to a negative health effect referred to as relative energy deficiency syndrome (REDs). This is an energy deficiency relative to the balance between dietary energy intake and energy availability required to support homeostasis, health and activities of daily living, growth and sporting activities that can result in multiple systems being affected including decreases in bone health, energy metabolism, reproductive function, musculoskeletal health, immunity, glycogen synthesis and cardiovascular and haematological health. The purpose of this study is to examine the prevalence of REDs in specific sports (combat sports and gymnastics) and dance genres (ballet and musical theatre). Voluntary participants will be tested three times a year over a 5-year period. This will include an annual dual-energy x-ray absorptiometry and blood tests plus resting energy expenditure and questionnaires three times a year.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Full-time training at either a NGB centre, dance company, vocational dance school or academy
Engaged in full-time training at start of project
Disqualifiers
Not engaged in full-time training
Injury preventing engagement in training
Trial population
Dancers: ballet, contemporary dance and musical theatre Combat sports: judo, karate, taekwondo Gymnastics: artistic
Trial design
Cohort
Prospective
Treatments tested in this trial
Dual x-ray scan
RadiationAnnual whole body scan monitoring bone mineral density for whole body, radius, L1-4 and femur and body composition
Blood screen
Diagnostic testThree times a year blood samples will be taken to measure: full blood count, ferritin, B12, folate, erythrocyte sedimentation rate (ESR), renal function, liver function, thyroid stimulating hormone (TSH), Free thyroxine (T4), luteinizing hormone (LH), oestradiol, testosterone, follicle-stimulating hormone (FSH), coeliac screen, vitamin D (25(OH)D), Leptin and Ghrelin
Questionnaires
Other interventionInformed consent; Low energy availability questionnaires for males and females; General health including menstrual status (females)
Anthropometric measurements
Other interventionThree times a year participant's measurements will be taken: stature, body mass and body composition (bio-impedence)
Resting Metabolic rate
Procedure/SurgeryResting metabolic rate will be measured by resting gas analysis. Each participant will lie down for a period of 15 minutes, in the final 5 minutes their expired gases are analysed using a breath-by-breath gas analyser (Cortex).
Energy expenditure
Other interventionEnergy expenditure was estimated using accelerometery (Genieactive) and activity logs in the participants' normal environment, assessed during 3 weekdays of scheduled dance training and 2 weekend days without scheduled dance training. Focus is on daily energy expenditure
Treatment groups
Trial outcomes
Primary outcomes
Relative energy deficiency (REDs)
Prevalence of REDs in cohorts by diagnosis by elimination by medical team.
Secondary outcomes
Bone stress injuries
Reported bone stress injuries by the inhouse medical teams
Primary Amenorrhea (females)
Loss of menses for at least 6 months
Resting Metabolic rate
Actual resting metabolic rate/estimated metabolic rate below 0.9
Monitoring of all blood markers for below normal values (red flags)
Blood markers: full blood count, ferritin, B12, folate, erythrocyte sedimentation rate (ESR), renal function, liver function, thyroid stimulating hormone (TSH), Free thyroxine (T4), luteinizing hormone (LH), oestradiol, testosterone, follicle-stimulating hormone (FSH), coeliac screen, vitamin D (25(OH)D), Leptin and Ghrelin
Sponsors and contacts
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