Relative Energy Deficiency in Sport and Dance

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-45
SponsorUniversity of Wolverhampton

About this trial

The International Olympic Committee recently published its consensus statement on relative energy deficiency syndrome (REDs) in sport which was followed by a similar version for dance by clinicians and researchers in dance. REDs is a complex multisystem syndrome with low energy availability as its foundation. Dancers and gymnasts, particularly in ballet, have long been reported to have body weight issues with an increase prevalence of eating disorders which has been associated with early onset osteoporosis. Combat sports have a similar issue, with athletes needing to "make weight" to compete in their ideal weight category that has lead to similar eating disorder and associated issues to dance. Currently there are no data on REDs prevalence in dance, gymnastics or combat sports and therefore understanding the underlying prevalence of REDs in both these populations will provide important information for both clinicians and coaches to help develop a safe and healthy environment for their dancers and athletes to compete/perform and to be able to retire from sport/dance without an increased risk of osteoporosis. In a few sports and dance genres, some participants might be more prone to a negative health effect referred to as relative energy deficiency syndrome (REDs). This is an energy deficiency relative to the balance between dietary energy intake and energy availability required to support homeostasis, health and activities of daily living, growth and sporting activities that can result in multiple systems being affected including decreases in bone health, energy metabolism, reproductive function, musculoskeletal health, immunity, glycogen synthesis and cardiovascular and haematological health. The purpose of this study is to examine the prevalence of REDs in specific sports (combat sports and gymnastics) and dance genres (ballet and musical theatre). Voluntary participants will be tested three times a year over a 5-year period. This will include an annual dual-energy x-ray absorptiometry and blood tests plus resting energy expenditure and questionnaires three times a year.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Full-time training at either a NGB centre, dance company, vocational dance school or academy

Engaged in full-time training at start of project

Disqualifiers

Not engaged in full-time training

Injury preventing engagement in training

Trial population

Dancers: ballet, contemporary dance and musical theatre Combat sports: judo, karate, taekwondo Gymnastics: artistic

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Dual x-ray scan

    Radiation

    Annual whole body scan monitoring bone mineral density for whole body, radius, L1-4 and femur and body composition

  • Blood screen

    Diagnostic test

    Three times a year blood samples will be taken to measure: full blood count, ferritin, B12, folate, erythrocyte sedimentation rate (ESR), renal function, liver function, thyroid stimulating hormone (TSH), Free thyroxine (T4), luteinizing hormone (LH), oestradiol, testosterone, follicle-stimulating hormone (FSH), coeliac screen, vitamin D (25(OH)D), Leptin and Ghrelin

  • Questionnaires

    Other intervention

    Informed consent; Low energy availability questionnaires for males and females; General health including menstrual status (females)

  • Anthropometric measurements

    Other intervention

    Three times a year participant's measurements will be taken: stature, body mass and body composition (bio-impedence)

  • Resting Metabolic rate

    Procedure/Surgery

    Resting metabolic rate will be measured by resting gas analysis. Each participant will lie down for a period of 15 minutes, in the final 5 minutes their expired gases are analysed using a breath-by-breath gas analyser (Cortex).

  • Energy expenditure

    Other intervention

    Energy expenditure was estimated using accelerometery (Genieactive) and activity logs in the participants' normal environment, assessed during 3 weekdays of scheduled dance training and 2 weekend days without scheduled dance training. Focus is on daily energy expenditure

Treatment groups

200 Participants
are divided into 3 treatment groups
Group A: Dance5 interventions
Group B: Combat Sports6 interventions
Group C: Gymnastics6 interventions

Trial outcomes

Primary outcomes

1

Relative energy deficiency (REDs)

Prevalence of REDs in cohorts by diagnosis by elimination by medical team.

Time frame
Throughout study; an average of 3 times a year

Secondary outcomes

1

Bone stress injuries

Reported bone stress injuries by the inhouse medical teams

Time frame
Number of participants with bone stress injuries. Throughout study an average of 3 times a year
2

Primary Amenorrhea (females)

Loss of menses for at least 6 months

Time frame
Number of participants with primary and secondary amenorrhea. Throughout study an average of 3 times a year
3

Resting Metabolic rate

Actual resting metabolic rate/estimated metabolic rate below 0.9

Time frame
Throughout study; an average of 3 times a year
4

Monitoring of all blood markers for below normal values (red flags)

Blood markers: full blood count, ferritin, B12, folate, erythrocyte sedimentation rate (ESR), renal function, liver function, thyroid stimulating hormone (TSH), Free thyroxine (T4), luteinizing hormone (LH), oestradiol, testosterone, follicle-stimulating hormone (FSH), coeliac screen, vitamin D (25(OH)D), Leptin and Ghrelin

Time frame
Throughout study; an average of 3 times a year

Other outcomes

Sponsors and contacts

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